Oxa(thia)zolidine compounds, process for preparation thereof and anti-inflammatory agents

摘要

The present invention provides medicinal compositions characterized by comprising as the active ingredient either a compound represented by a formula [I] or a pharmaceutically acceptable composite thereof; [wherein X represents oxygen or sulfur; R₁ represents e.g., C_1-4 alkyl, phenyl optionally substituted, etc.; Q₁ represents spacer consisted of 0 to 3 carbon atoms; R₂ represents, e.g., phenyl optionally substituted; R₃ represents, e.g., hydrogen, C_1-4 alkyl, or a group represented by the following formulae; -CONH-R₆; R₄ and R₅ represent e.g., nitro, cyano, C_1-4 alkylcarbonyl, respectively]; in particular, medicine which is useful as therapeutic and/or protective drugs for inflammatory diseases and/or allergic diseases by improving sick conditions accompanied with the stimulated phospholipase A(2) activity.