The present disclosure is directed towards improved systems and methods for large-scale production of nanoparticles used for delivery of therapeutic material. The apparatus can be used to manufacture a wide array of nanoparticles containing therapeutic material including, but not limited to, lipid nanoparticles and polymer nanoparticles. In certain embodiments, continuous flow operation and parallelization of microfluidic mixers contribute to increased nanoparticle production volume.
申请公布号
WO2016138175(A1)
申请公布日期
2016.09.01
申请号
WO2016US19414
申请日期
2016.02.24
申请人
THE UNIVERSITY OF BRITISH COLUMBIA
发明人
RAMSAY, Euan;TAYLOR, Robert James;LEAVER, Timothy;WILD, Andre;OU, Kevin;WALSH, Colin