摘要 |
<p>A B S R A C T The invention relates to processes for preparing 1-oxo-2-phenyl, halophenyl or thienyl-2-methyl-6,7-dichloro-5-indanyloxy!acetic acid, which have diuretic, saluretic and uricosuric activity. The process involves the use of novel ubterneduates having the structures: where R2 is phenyl, halophenyl or theinyl and R is CH2COOH, R1 or CH2COOR1 where, R1 is lower alkyl or haloloweralkyl, aryl and nuclear substituted derivatives aralkyl having from 7 to 20 carbon atoms, and X is OH, halo, and acid ester moieties.</p> |