发明名称 PROCESS FOR PREPARING (1-OXO-2-PHENYL, HALOPHENYL OR THIENYL-2-METHYL-6,7-DICHLORO-5-INDANYLOXY)ACETIC
摘要 <p>A B S R A C T The invention relates to processes for preparing 1-oxo-2-phenyl, halophenyl or thienyl-2-methyl-6,7-dichloro-5-indanyloxy!acetic acid, which have diuretic, saluretic and uricosuric activity. The process involves the use of novel ubterneduates having the structures: where R2 is phenyl, halophenyl or theinyl and R is CH2COOH, R1 or CH2COOR1 where, R1 is lower alkyl or haloloweralkyl, aryl and nuclear substituted derivatives aralkyl having from 7 to 20 carbon atoms, and X is OH, halo, and acid ester moieties.</p>
申请公布号 CA1039295(A) 申请公布日期 1978.09.26
申请号 CA19740210648 申请日期 1974.10.03
申请人 MERCK & CO., INC. 发明人 RUSS, WARREN K. (JR.);HAZEN, GEORGE G.;CHAMBERLIN, EARL M.
分类号 A61K31/12;A61K31/19;A61K31/22;A61P7/10;A61P19/06;C07C45/46;C07C45/66;C07C45/75;C07C49/755;C07C49/84;C07C51/00;C07C51/367;C07C59/125;C07C59/90;C07C67/00;C07D211/46;C07D333/22;(IPC1-7):07C51/00;07D333/22 主分类号 A61K31/12
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