| 摘要 |
PURPOSE:To inexpensively carry out ozone decomposition without danger of explosion even under conditions of high temperature and obtain the title compound in reduce cooling cost and high yield by carrying out ozone decomposition of an organic unsaturated compound in the presence of a Lewis acid. CONSTITUTION:An organic unsaturated compound expressed by formula I [R<1> is lower alkoxy, lower alkyl, azetidinyl, azetidinyl-lower alkyl, etc.; R<2> is H, carboxyl, lower alkyl, lower alkoxycarbonyl, etc.; R<3> is H, phenyl or lower alkyl; R<4> is H or lower alkyl, provided that R<1> is mutually combined with R<2> to form azetidinylidene substituent group; R<2> is mutually combined with R<3> to form lower alkenylene substituent group] is subjected to ozone decomposition with introduced ozone gas in an inert solvent, e.g. mixed solvent such as methylene chloride and methanol in the presence of a Lewis acid such as CaCl2, preferably at -5 to 0 deg.C for 30 min to 3 hr to provide the aimed compound expressed by formula II and formula III. |
