发明名称 |
Substituted 2,2-dimethyl-omega-phenoxy alkanoic acids and esters, process for their preparation and pharmaceutical compositions containing them |
摘要 |
<p>2,2-Dimethyl- omega -phenoxy-alkanoic acid derivs. of formula (I) and their isomers and salts are new. In (I), X = O, S or a single bond; A = single bond or 1-9C (un)branched hydrocarbon gp. opt. contg. double bond or O atom; B = 1-9C (un)branched hydrocarbon gp.; R = H or 1-6C alkyl opt. substd. by 1 or 2 OH gps.; R1 = H or Me and R3 = H; or R3 = H and R1 = single bond forming double bond with hydrocarbon gp. A; or R1+R3 = CH2 or CH2CH2 except where X = single bond; R2, R6 = H or Me; R4, R5 = 1-6C alkyl; R7 = H or protecting gp. (e.g. COMe, CH2OEt or benzyl); and Z = H, halo, 1-5C alkyl or 1-5C alkoxy.</p> |
申请公布号 |
EP0763527(A1) |
申请公布日期 |
1997.03.19 |
申请号 |
EP19960401946 |
申请日期 |
1996.09.12 |
申请人 |
ADIR ET COMPAGNIE |
发明人 |
REGNIER, GILBERT;GUILLONNEAU, CLAUDE;VILAINE, JEAN-PAUL;MAHLBERG, FLORENCE;BREUGNOT, CHRISTINE |
分类号 |
C07D335/06;A61K31/19;A61K31/215;A61K31/35;A61K31/352;A61K31/38;A61K31/382;A61P3/06;A61P3/08;A61P3/10;A61P9/10;A61P43/00;C07C51/377;C07C59/68;C07C67/31;C07C69/734;C07C319/14;C07C323/20;C07D311/72;(IPC1-7):C07C323/16 |
主分类号 |
C07D335/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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