发明名称 |
Ihmisen follikkelia stimuloivan hormonin reseptori |
摘要 |
The present invention embraces essentially pure human FSH receptor, or a fragment or mutant thereof which binds FSH, DNA encoding said receptor, fragment or mutant, expression vectors comprising said DNA, cells transfected with said expression vectors, and methods of producing said receptor, fragment or mutant by culturing said transfected cells. The present invention also includes pharmaceutical compositions comprising said receptor, fragment or mutant, was well as methods of treating patients with such compositions to reduce endogenous FSH bioactivity. An improved assay for human FSH using the receptor, fragment or mutant of the present invention is also disclosed.
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申请公布号 |
FI109360(B) |
申请公布日期 |
2002.07.15 |
申请号 |
FI19930004023 |
申请日期 |
1993.09.14 |
申请人 |
APPLIED RESEARCH SYSTEMS ARS HOLDING N.V., |
发明人 |
KELTON,CHRISTIE ANN;CHENG,SHIRLEY VUI YEN;NUGENT,NOREEN PATRICE;SCHWEICKHARDT,RENE LYNN |
分类号 |
A61K38/00;A61K38/17;A61P5/06;A61P13/02;A61P15/00;A61P15/16;C07K14/00;C07K14/705;C07K14/72;C12N5/10;C12N15/09;C12N15/12;C12P21/02;C12R1/91;G01N33/74;(IPC1-7):C12N15/12;C07K14/59;A61K38/24 |
主分类号 |
A61K38/00 |
代理机构 |
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主权项 |
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地址 |
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