| 发明名称 |
HETEROARYL UREA DERIVATIVES USEFUL FOR INHIBITING CHKL |
| 摘要 |
<p num="1"><br/><br/><br/>Substituted urea compounds useful in the treatment of diseases and conditions <br/>related to DNA damage or lesions in DNA replication are disclosed. Methods of <br/>making the compounds, and their use as therapeutic agents, for example, in <br/>treating cancer and other diseases characterized by defects in DNA <br/>replication, chromosome segregation, or cell division, also are disclosed.<br/>
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| 申请公布号 |
CA2602199(A1) |
申请公布日期 |
2006.10.05 |
| 申请号 |
CA20062602199 |
申请日期 |
2006.03.29 |
| 申请人 |
ICOS CORPORATION |
发明人 |
KESICKI, EDWARD A.;THORSETT, EUGENE;GAUDINO, JOHN JOSEPH;FISCHER, KIMBA L.;FAROUZ, FRANCINE S.;COOK, ADAM WADE;HOLCOMB, RYAN;OOI, HUA CHEE;DIAZ, FRANK;RUDOLPH, ALEXANDER;STAPPENBECK, FRANK |
| 分类号 |
C07D403/12;A61K31/497;A61K31/5355;A61K31/541;A61P35/00;C07D413/12;C07D417/12 |
主分类号 |
C07D403/12 |
| 代理机构 |
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