PARTICLES FOR DELIVERY OF BIOACTIVE FACTORS

摘要

Provided herein are cell-responsive biodegradable microparticles, comprising a hydrophilic polymer crosslinked with a crosslinking group which is degradable by a releasing species produced by a cell and a binding species coupled to the polymer for binding and delivering a bioactive factor, such as a growth factor, to a cell. Also provided are methods of synthesis of cell-responsive biodegradable microparticles.