发明名称 |
DERIVATIVES OF 5-BENZYLISOQUINOLINE FOR THE TREATMENT OF CARDIOVASCULAR DISEASES |
摘要 |
The invention relates to novel isoquinoline derivatives of formula (I), to the synthesis thereof, and to the use of same in the prevention and/or treatment of pathologies resulting from the activation of the RhoA/ROCK pathway and the phosphorylation of the light chain of myosin. X represents a group -C(=0)-, -CH(OH)- or -CH2-, and the other substituents represent various groups such as those defined in claim 1. |
申请公布号 |
SG11201605662T(A) |
申请公布日期 |
2016.08.30 |
申请号 |
SGT11201605662 |
申请日期 |
2015.02.20 |
申请人 |
LES LABORATOIRES SERVIER |
发明人 |
CHIMENTI, STEFANO;COURCHAY, CHRISTINE;DESSINGES, AIMÉE;GELLIBERT, FRANÇOISE;GOUMENT, BERTRAND;KONNERT, MARC;PEGLION, JEAN-LOUIS;POITEVIN, CHRISTOPHE;VILAINE, JEAN-PAUL;VILLENEUVE, NICOLE |
分类号 |
C07D217/02;A61K31/472;A61P9/00;C07D217/24;C07D405/06 |
主分类号 |
C07D217/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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