发明名称 |
4-(5-(4-chlorophenyl)-2-(2-cyclopropylacetyl)-1,4-dimethyl-1H-pyrrol-3-yl)benzenesulfonamide as alpha 7 nAChR modulator |
摘要 |
Disclosed are an alpha 7 nAChR receptor modulator compound, 4-(5-(4-chlorophenyl)-2-(2-cyclopropylacetyl)-1,4-dimethyl-1H-pyrrol-3-yljbenzenesulfonamide, its tautomeric form, its pharmaceutically acceptable salts, pharmaceutical compositions comprising the compound or a salt thereof, and a method of treating various diseases, disorders or conditions, for example, Alzheimer's disease, mild cognitive impairment, senile dementia, vascular dementia, dementia of Parkinson's disease, and attention deficit disorder. |
申请公布号 |
US9447037(B2) |
申请公布日期 |
2016.09.20 |
申请号 |
US201414894803 |
申请日期 |
2014.06.02 |
申请人 |
Lupin Limited |
发明人 |
Sinha Neelima;Karche Navnath Popat;Tilekar Ajay Ramchandra;Palle Venkata P.;Kamboj Rajender Kumar |
分类号 |
C07D207/335;C07D207/333;A61K31/40;A61K45/06 |
主分类号 |
C07D207/335 |
代理机构 |
Leydig, Voit & Mayer, Ltd. |
代理人 |
Leydig, Voit & Mayer, Ltd. |
主权项 |
1. 4-(5-(4-chlorophenyl)-2-(2-cyclopropylacetyl)-1,4-dimethyl-1H-pyrrol-3-yl)benzenesulfonamide, a tautomer thereof, or a pharmaceutically acceptable salt thereof. |
地址 |
Mumbai IN |