发明名称 |
Treatment of Multiple Sclerosis With Combination of Laquinimod and Interferon-Beta |
摘要 |
This invention provides a method of treating a patient afflicted with multiple sclerosis or presenting a clinically isolated syndrome comprising administering to the patient laquinimod as an add-on therapy to or in combination with interferon-β. This invention also provides a package and a pharmaceutical composition comprising laquinimod and interferon-β for treating a patient afflicted with multiple sclerosis or presenting a clinically isolated syndrome. This invention also provides laquinimod for use as an add-on therapy or in combination with interferon-β in treating a patient afflicted with multiple sclerosis or presenting a clinically isolated syndrome. This invention further provides use of laquinimod and interferon-β in the preparation of a combination for treating a patient afflicted with multiple sclerosis or presenting a clinically isolated syndrome. |
申请公布号 |
US2016166648(A1) |
申请公布日期 |
2016.06.16 |
申请号 |
US201615050005 |
申请日期 |
2016.02.22 |
申请人 |
Gilgun Yossi;Tarcic Nora |
发明人 |
Gilgun Yossi;Tarcic Nora |
分类号 |
A61K38/21;A61K9/00;A61K47/18;A61K47/02;A61K47/26;A61K31/4704;A61K45/06 |
主分类号 |
A61K38/21 |
代理机构 |
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代理人 |
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主权项 |
1. A method of treating a human patient afflicted with multiple sclerosis or presenting a clinically isolated syndrome comprising orally administering to the patient a daily dose of 0.6 mg laquinimod, and periodically administering to the patient a pharmaceutically effective amount of interferon-β, wherein the amounts when taken together is more effective to treat the human patient than when each agent is administered alone. |
地址 |
Bat Hefer IL |