| 摘要 |
Provided are compositions comprising a collection of overcoated particles wherein each of the overcoated particles comprises a first coating and a second coating. In one embodiment, the first coating comprises water insoluble material, for example a fatty compound or a waxy material. In another embodiment, the second coating comprises a water insoluble polymer or water resistant film, wherein the water insoluble polymer of the second coating is different than the water insoluble material of the first coating. Also provided is a slurry comprising water and overcoated powders provided herein. Also provided is a method of contacting plants or plant parts with a composition or slurry provided herein. Provided are compositions comprising a collection of overcoated particles wherein each of the overcoated particles comprises a first coating and a second coating. In one embodiment, the first coating comprises water insoluble material, for example a fatty compound or a waxy material. In another embodiment, the second coating comprises a water insoluble polymer or water resistant film, wherein the water insoluble polymer of the second coating is different than the water insoluble material of the first coating. Also provided is a slurry comprising water and overcoated powders provided herein. Also provided is a method of contacting plants or plant parts with a composition or slurry provided herein. In its many embodiments, the present invention provides certain C2-azaspirosubstituted iminothiazine dioxide compounds. The novel compounds of the invention are useful as BACE inhibitors and/or for the treatment and prevention of various pathologies related thereto. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use, including for the possible treatment of Alzheimer's disease, are also disclosed. |
