发明名称 COMPOSITION FOR ORAL CAVITY
摘要 PURPOSE:To prepare a composition for oral cavity, having high aseptic activity and excellent storage stability, by adding a surface active agent to a base containing a water-soluble calcium salt. CONSTITUTION:A water-soluble calcium salt having a solubility of >=0.3wt%, especially >=1wt% in distilled water at 25 deg.C (preferably calcium lactate or calcium gluconate) is dissolved or dispersed in water or a water-containing liquid, and the solution or dispersion is mixed with other ingredients to obtain a base of the composition for oral cavity. The obtained base is incorporated with a surface active agent, preferably an anionic surface active agent (especially alkyl sulfuric acid ester metal salt) or a nonionic surface active agent (especially sucrose fatty acid ester). The preferable amounts of the calcium salt and the surface active agent are 0.5-5wt% and 0.1-5wt%, respectively, based on the whole composition. Addition of 0.01-1wt% of p-hydroxybenzoic acid alkyl ester (especially methyl ester) improves the aseptic activity without deteriorating the taste, etc. of the product.
申请公布号 JPS58216114(A) 申请公布日期 1983.12.15
申请号 JP19820098691 申请日期 1982.06.09
申请人 RAION KK 发明人 ISHIKAWA MASAO;NAGAI IZUMI;YOSHIKAWA MASARU;WATANABE TOSHIYUKI
分类号 A61K8/00;A61K8/19;A61K8/33;A61K8/36;A61K8/365;A61K8/73;A61Q11/00 主分类号 A61K8/00
代理机构 代理人
主权项
地址