| 发明名称 |
P40 HOMODIMER (TWO ASSOCIATED P40 SUBUNITS) OF INTERLEUKIN 12, ITS PREPARATION AND COMPOSITIONS THEREOF |
| 摘要 |
<p>The present invention is directed towards a protein comprising two p40 subunits of interleukin-12 which are associated together, preferably by at least one disulfide bond, having a molecular weight of about 80 kDa. The 80 kDa p40 homodimer acts as an interleukin-12 receptor antagonist. The preferred p40 subunit is that of SEQ ID NO:1.</p> |
| 申请公布号 |
NZ260843(A) |
申请公布日期 |
1996.02.27 |
| 申请号 |
NZ19940260843 |
申请日期 |
1994.06.24 |
| 申请人 |
F HOFFMANN-LA ROCHE AG |
发明人 |
GATELY, MAURICE KENT;HAKIMI, JOHN;LING, PING |
| 分类号 |
A61K38/00;A61K38/19;A61K38/20;A61P3/08;A61P9/00;A61P29/00;A61P37/06;A61P43/00;C07K1/22;C07K14/52;C07K14/54;C07K19/00;C12N5/10;C12N15/00;C12N15/09;C12N15/24;C12P21/02;(IPC1-7):C07K14/715;C07K1/36;A61K38/17 |
主分类号 |
A61K38/00 |
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