发明名称 |
Identification of CXCR8, a novel chemokine receptor |
摘要 |
Method of treating a subject for a disorder that correlates to increased CXCR8 signaling. The method includes disrupting the activation of receptor CXCR8 by ligand CXCL17 in the subject. In the method, the disrupting can include administering to the subject a substance that interferes with CXCL17 binding to CXCR8. Methods of screening, ligands, agonists, antagonists and vaccines involving the CXCR8/CXCL17 axis are also provided. |
申请公布号 |
AU2014324408(A8) |
申请公布日期 |
2016.06.30 |
申请号 |
AU20140324408 |
申请日期 |
2014.09.30 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
ZLOTNIK, ALBERT;MARAVILLASMONTERO, JOSE L.;BURKHARDT, AMANDA M. |
分类号 |
C12Q1/68;C12N15/11;G01N33/53;G01N33/567 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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