A vehicle chassis inspection method and system. The method comprises the steps of: acquiring a chassis image of a vehicle under inspection; acquiring a chassis image template of a vehicle with the same vehicle model as that of the vehicle from a database; performing registration on the chassis image of the vehicle under inspection and the chassis image template; differentiating the registered chassis image and the registered chassis image template, so as to obtain a change region of the chassis image of the vehicle relative to the chassis image template; and presenting the change region. By automatically detecting hidden entrainments from a chassis image by means of image processing and mode recognition, this method can be applied to the security inspection field.