| 发明名称 |
Anti-cancer nanoparticle compositions and methods of use |
| 摘要 |
The present invention encompasses a composition capable of delivering and expressing a nucleic acid encoding UDP-Glucuronosyltransferases, p53 or a combination thereof into a cell, and methods for treating tumors. |
| 申请公布号 |
US9399055(B2) |
申请公布日期 |
2016.07.26 |
| 申请号 |
US201414336492 |
申请日期 |
2014.07.21 |
| 申请人 |
Board of Trustees of the University of Arkansas |
发明人 |
Radominska-Pandya Anna;Biris Alexandru S. |
| 分类号 |
C12N5/00;C12N5/02;A61K48/00;A61K38/45;A61K31/711;A61K38/17;A61K47/48;B82Y5/00;A61K9/00 |
主分类号 |
C12N5/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An isolated pancreatic tumor cell, wherein the tumor cell comprises at least one nucleic acid attached to a nanoparticle, wherein the at least one nucleic acid is a nucleic acid encoding UGT2B15, and the nanoparticle is selected from the group consisting of a carbon nanotube, carbon nanorod, and carbon nanosphere, such that the nucleic acid is expressed within the pancreatic tumor cell. |
| 地址 |
Little Rock AR US |
