发明名称 SULPHAMOYLGUANIDINE DERIVATIVES
摘要 Described are compounds of formula XLI <CHEM> with R, R<4><2> and R<4><3> being hydrogen, alkyl, phenyl or phenalkyl being phenyl furyl, thiazolyl or thiadiazolyl; X being oxygen or sulphur; n being 0 or 1; and m being 2, 3 or 4. Described is a process for their production reacting compounds XLIII <CHEM> (L being X-alkyl or X-phenylalkyl with compound XLV A - (CH2)n - X - (CH2)m - NH2 XLV or reacting compound XLIV <CHEM> with HNR<4><2>R<4><3> XLVI. Compounds XLI are valuable H-2 antagonists.
申请公布号 AU4045585(A) 申请公布日期 1986.01.30
申请号 AU19850040455 申请日期 1985.03.26
申请人 HOECHST UK LTD. 发明人 SIMON JOHN COUSINS;JEFFREY DANIEL MICHAEL;BARRY CLIVE ROSS
分类号 C07D307/38;A61K31/16;A61K31/165;A61K31/34;A61K31/341;A61K31/345;A61K31/425;A61K31/426;A61K31/433;A61K31/445;A61P43/00;C07C67/00;C07C301/00;C07C303/40;C07C307/04;C07C307/06;C07C333/00;C07C335/38;C07D277/22;C07D277/48;C07D285/04;C07D285/08;C07D295/08;C07D295/096;C07D417/12 主分类号 C07D307/38
代理机构 代理人
主权项
地址