发明名称 Antisense composition and method for treating cancer
摘要 A method and composition for treating colorectal cancer is disclosed. The method involves administering to a subject, a therapeutically effective amount of a morpholino antisense compound (i) having a nuclease-resistant backbone, (ii) capable of uptake by target cancer cells in the subject, (iii) containing between 10-40 nucleotide bases, and (iv) having a base sequence effective to hybridize to a region of processed or preprocessed human SNAIL RNA transcript.
申请公布号 US7402574(B2) 申请公布日期 2008.07.22
申请号 US20050077871 申请日期 2005.03.10
申请人 AVI BIOPHARMA, INC. 发明人 IVERSEN PATRICK L.;ROY HEMANT K.;BESTWICK RICHARD K.
分类号 A61K31/70;A61K48/00;C07H21/04;C12N15/113;C12N15/85 主分类号 A61K31/70
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