METHODS, SYSTEMS, AND COMPOSITIONS FOR PROMOTING BONE GROWTH

摘要

The present invention relates to novel bone compositions for locally delivering a therapeutic agent to the site of a bone defect. Therapeutic agents may promote repair of the bone defect and/or treat conditions or disorders such as pain, inflammation, cancer, and infection. The compositions include calcium phosphate cements and a demineralized bone matrix or a collagen sponge. The compositions are useful for implantation in a patient at the site of a bone defect.

主权项

1. A bone composition comprising:
a drug-carrier mixture, the drug-carrier mixture comprising a therapeutically effective amount of a drug and a calcium phosphate cement; and a collagen sponge or a bone matrix, the bone matrix being at least partially demineralized.