| 发明名称 |
High Concentration Antibody Formulations |
| 摘要 |
Discloses herein are high concentration antibody formulations comprising an anti-sclerostin immunoglobulin and an acetate salt and/or an acetate buffer and methods of use. |
| 申请公布号 |
US2016235849(A1) |
申请公布日期 |
2016.08.18 |
| 申请号 |
US201615144256 |
申请日期 |
2016.05.02 |
| 申请人 |
AMGEN INC. |
发明人 |
Osslund Timothy D. |
| 分类号 |
A61K47/14;A61K39/395 |
主分类号 |
A61K47/14 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A sterile liquid formulation that has an absolute viscosity of about 10 cP or less comprising: (a) an anti-sclerostin immunoglobulin at a concentration of at least 70 mg/mL; and (b) calcium acetate at a concentration ranging from about 1 mM to about 20 mM. |
| 地址 |
Thousand Oaks CA US |
