发明名称 |
MEMBRANE AFFINITY APPARATUS AND PURIFICATION METHODS RELATED THERETO |
摘要 |
The invention relates to an apparatus useful for the separation of at least one preselected ligate present in a fluid. The invention also features an easily scaled-up membrane affinity separation process which is highly reliable, highly selective, provides a high yield of product, and is further characterized by a high volumetric throughput. The invention utilizes a substantially isotropic porous membrane, to which is associated a preselected ligand, which provides an optimum loading capacity and low dead volume while allowing high filtrate flow rates. Methods for isolating macromolecules having therapeutic value are described. |
申请公布号 |
WO9005018(A1) |
申请公布日期 |
1990.05.17 |
申请号 |
WO1989US04847 |
申请日期 |
1989.10.30 |
申请人 |
SEPRACOR, INC. |
发明人 |
GOFFE, RANDAL, A.;ZALE, STEPHEN, E.;O'CONNOR, JAMES, L.;KESSLER, STEPHEN, B.;COHEN, CHARLES, M. |
分类号 |
B01D15/08;B01D61/00;B01D63/02;B01D63/04;B01D63/08;B01D67/00;B01D69/08;B01D69/14;B01J16/00;C07K1/00;C07K1/22;C07K14/745;C07K14/755;C07K14/78;C07K16/00;C07K16/06;C07K16/36;C07K16/40;C12N9/64;D01D5/24;G01N30/52 |
主分类号 |
B01D15/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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