| 摘要 |
<p>The invention concerns quinazoline derivatives of Formula (I) wherein Z is an O, S, SO, SO2, N(R<2>) or C(R<2>)(R<3>) group wherein each R<2> or R<3> group is hydrogen or (1-8C)alkyl, m is 1, 2 or 3, each R<1> group is selected from halogeno, (1-8C)alkyl, (1-6C)alkoxy and any of the other meanings defined in the description, R<a> is hydrogen or halogeno, R<b> is hydrogen, halogeno, (1-6C)alkyl or (1-6C)alkoxy, R<c> is hydrogen, halogeno, (1-8C)alkyl or (1-6C)alkoxy, and R<d> is (1-6C)alkoxy, or pharmaceutically-acceptable salts thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an anti-invasive agent in the containment and/or treatment of solid tumour disease.</p> |
