| 发明名称 |
Human and rat PGC-3, PPAR-gamma coactivations and splice variants thereof |
| 摘要 |
A novel gene PGC-3, and its role in regulating the transcriptional activity of PPARgamma in adipose tissue. PGC-3 is highly expressed in human white adipose tissue and has utility in the development of new therapeutic agents for use in the treatment of obesity and other related disorders such as non-insulin dependent diabetes mellitus, insulin resistance syndrome, dyslipidemia, and atherosclerosis.
|
| 申请公布号 |
US7306922(B2) |
申请公布日期 |
2007.12.11 |
| 申请号 |
US20030380492 |
申请日期 |
2003.03.13 |
| 申请人 |
ASTRAZENECA AB |
发明人 |
HART KEVIN ANTHONY;MONTAGUE CARL THOMAS;VIDAL-PUIG ANTONIO |
| 分类号 |
G01N33/50;G01N33/53;A61K38/00;A61K45/00;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P9/10;C07H21/04;C07K14/47;C07K14/575;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/12;G01N33/15;G01N33/566 |
主分类号 |
G01N33/50 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
