USE OF MOLECULAR WEIGHT-ENLARGED CATALYST IN PROCESS FOR ASYMMETRIC, CONTINUOUS HYDROGENATION, NOVEL MOLECULAR WEIGHT-ENLARGED LIGAND AND CATALYST

摘要

PROBLEM TO BE SOLVED: To enable the lowering of production cost by providing the use of molecular weight-enlarged, homogeneously soluble catalysts in a membrane reactor in a process for the asymmetric, continuous hydrogenation of C=C, C=N or C=0 double bonds, novel molecular weight-enlarged ligands, and asymmetric hydrogenation catalysts. SOLUTION: The ligands, catalysts, active centre, and their uses, comprises ligands such as polyacrylates, polystyrene, polysiloxanes or polyacrylates as molecular weight-enlarging agents, having an average molecular weight of 1,000 to 1,000, 000 g/mole, a metal or metal ion selected from Ru, Rh, Ir, Pd, Ni, Pt, and Co, and a representative example is N,N'-bis(2- diphenylphosphanylbenzyl) cyclohexyl-1,2-diamine as the asymmetric synthesis active center of the ligand, or the like.