发明名称 |
AN HIV-1 LATENCY MODEL FOR HIGH THROUGHPUT SCREENING |
摘要 |
Isolated, latently infected T cell lines are provided that can be utilized in high throughput screening to discover compounds capable of activating HIV-I. The T cell lines harbor a latent HIV-I derived vector pro virus, which upon activation expresses a marker for late viral gene expression due to the insertion of the marker gene in the position of HIV-I envelope. |
申请公布号 |
CA2632456(C) |
申请公布日期 |
2016.06.21 |
申请号 |
CA20062632456 |
申请日期 |
2006.11.27 |
申请人 |
UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY |
发明人 |
DOUGHERTY, JOSEPH P.;MICHEVA-VITEVA, SOFIYA;PELTZ, STUART W.;RON, YACOV;PACCHIA, ANNMARIE L. |
分类号 |
C12N5/10;C12N7/01;C12N15/867;C12Q1/70 |
主分类号 |
C12N5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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