| 发明名称 |
ORALLY DISINTEGRATING TABLET COMPOSITIONS OF LAMOTRIGINE |
| 摘要 |
The compositions of the present invention composition comprise a therapeutically effective amount of particles comprising lamotrigine, in combination with granules comprising a disintegrant, and a sugar alcohol and/or a saccharide. These compositions are useful in treating epilepsy and bipolar disorder, particularly for patients with dysphagia, and to improve compliance with bipolar patients. |
| 申请公布号 |
US2016256464(A1) |
申请公布日期 |
2016.09.08 |
| 申请号 |
US201615155960 |
申请日期 |
2016.05.16 |
| 申请人 |
ADARE Pharmaceuticals, Inc. |
发明人 |
Venkatesh Gopi M.;Vyas Nehal H.;Gosselin Michael;Lai Jin-Wang |
| 分类号 |
A61K31/53;A61K9/50;A61K9/20;A61K9/00 |
主分类号 |
A61K31/53 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An orally dissolving or disintegrating (ODT) composition comprising a therapeutically effective amount of lamotrigine, wherein after administration said composition substantially disintegrates in the oral cavity of a patient and provides a lamotrigine release profile which is substantially the same as the lamotrigine release profile of an immediate release lamotrigine composition. |
| 地址 |
Lawrenceville NJ US |
