| 摘要 |
Method for the prevention or treatment of pruritus with anti-pruritic compounds is provided.The compounds of formulae I, II, IIA, III, IIIA, IV and IVA have the structure:whereinR1, R2, R3, R4; andX, X4, X5, X7, X9;Y, Z and n are as described in the specification.
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