| 摘要 |
The present invention relates to compounds of Formula (I), methods for pr eparing these compounds, compositions, intermediates and derivatives thereof and for treating a condition including but not limited to ankylosing spondy litis, artherosclerosis, arthritis (such as rheumatoid arthritis, infectious arthritis, childhood arthritis, psoriatic arthritis, reactive arthritis), b one-related diseases (including those related to bone formation), breast can cer (including those unresponsive to anti-estrogen therapy), cardiovascular disorders, cartilage-related disease (such as cartilage injury/loss, cartila ge degeneration, and those related to cartilage formation), chondrodysplasia , chondrosarcoma, chronic back injury, chronic bronchitis, chronic inflammat ory airway disease, chronic obstructive pulmonary disease, diabetes, disorde rs of energy homeostasis, gout, pseudogout, lipid disorders, metabolic syndr ome, multiple myeloma, obesity, osteoarthritis, osteogenesis imperfecta, ost eolytic bone metastasis, osteomalacia, osteoporosis, Paget's disease, period ontal disease, polymyalgia rheumatica, Reiter's syndrome, repetitive stress injury, hyperglycemia, elevated blood glucose level, and insulin resistance.
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