| 主权项 |
1. A monoclonal anti-Prodefensin-A6 antibody that (i) is specific for the propeptide of the Prodefensin-A6 protein, or (ii) recognizes an epitope including an amino acid sequence selected from the group consisting of the amino acid sequences of:
(a) X1X2X3X4X5X6X7X8R (SEQ ID NO: 7), in which X1 is V or L, X2 is T or L, X3 is P, S or C, X4 is P or S, X5 is W or T, X6 is A, Q, M, C or E, X7 is I, E or D and X8 is F, Y, S or L; (b) X1X2X3X4X5X6HX7 (SEQ ID NO: 13), in which X1 is S or T, X2 is C or absent, X3 is T, L or E, X4 is H or R, X5 is I, F or E, X6 is G or V and X7 is C or N; (c) X1HPX2X3X4X5X6X7 (SEQ ID NO: 17), in which X1 is P or W, X2 is W or E, X3 is S, A, Q or W, X4 is M, L, R or P, X5 is H, F, W or G, X6 is V or A and X7 is I or V; and (d) X1HX2X3X4X5 (SEQ ID NO: 22), in which X1 is Y or N, X2 is E, D or Q, X3 is T, N, R, M or K, X4 is W, H or F and X5 is P or G. |
