Microorganism for selective production of a specific compound of avermectin and a method for selective production thereof

摘要

A microorganism for selective production of a specific compound of avermectin having one or more of the following properties: specific accumulation of avermectin compound "a", effective incorporation of isoleucine or its keto acid (3-methyl-2-oxovaleric acid) into avermectin molecule, and markedly suppressed incorporation of valine or its keto acid (2-oxoisovaleric acid) into avermectin molecule.