发明名称 ANTIBODY TO HEPATITIS GB VIRUS EPITOPE AND USE THEREOF
摘要 PROBLEM TO BE SOLVED: To obtain an antibody excellent in assay accuracy ad useful for diagnostics, kits, vaccines, etc., by setting against hepatitis GB virus(HGBV) epitope(s). SOLUTION: This antibody is such one as to stand against at least one kind of Hepatitis GB virus(HGBV) epitope, being pref. a polyclonal or monoclonal antibody. This antibody is obtained by administering an individual with an isolated immunogenic polypeptide (or a fragment thereof) containing at least one HGBV epitope at an amount enough to induce immune response. Furthermore, it is preferable that a suspectable test sample containing HGBV is contacted with an antibody (fragment) specifically bindable to at least one HGBV antigen for an enough time and under sufficient conditions to form an antibody/antigen complex to detect an antibody-contg. complex to detect a HGBV antigen in the test sample.
申请公布号 JPH10337193(A) 申请公布日期 1998.12.22
申请号 JP19980111629 申请日期 1998.03.31
申请人 ABBOTT LAB 发明人 SIMONS JOHN N;PILOT-MATIAS TAMI J;DAWSON GEORGE J;SCHLAUDER GEORGE G;DESAI SURESH M;LEARY THOMAS P;MUERHOFF ANTHONY SCOTT;ERKER JAMES CARL;BUIJK SHERI L;MUSHAHWAR ISA K
分类号 G01N33/564;A61K38/00;A61K39/29;A61K39/395;A61P1/16;A61P31/12;C07H21/04;C07K7/06;C07K7/08;C07K14/08;C07K14/18;C07K16/10;C12N5/10;C12N7/00;C12N15/09;C12P21/02;C12P21/08;C12Q1/68;C12Q1/70;C12R1/19;G01N33/576;G01N33/577 主分类号 G01N33/564
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