AURONE DERIVATIVE-CONTAINING COMPOSITION FOR DIAGNOSIS.

摘要

A composition for the diagnosis of diseases relating to amyloid which contains either a compound represented by the general formula (I): [wherein X represents O, etc.; R¹, R³, R⁴, R⁵, R⁶, R⁸, and R⁹ each represents hydrogen, etc.; R² represents halogeno, etc.; and R⁷ represents dimethylamino, etc.] or a compound obtained by labeling that compound with a radionuclide or contains a pharmaceutically acceptable salt of any of these compounds. The compound represented by the general formula (I) has high bonding specificity for amyloid ÿ-protein, is apt to highly pass through the blood-brain barrier, and has the property of rapidly disappearing from the areas excluding senile plaques in the brain.