O-ANTIGEN CARBOHYDRATE CHAIN EXTENDED S ALMONELLA PARATYPHI A AND USE THEREOF

摘要

Provided are an O-antigen carbohydrate chain extended Salmonella paratyphi A and a use thereof. The method comprises the following steps: inactivating a cld geneof the enzyme for controlling the O-antigen chain length of Salmonella paratyphi A, and obtaining Salmonella paratyphi A defects in a cld gene of the enzyme for controlling the O-antigen chain length; overexpressing a cld LT2 gene of the enzyme for controlling the O-antigen chain length of Salmonella typhimurium in the Salmonella paratyphi A defects in the cld gene of the enzyme for controlling the O-antigen chain length, and then extending the O-antigen carbohydrate chain length of Salmonella paratyphi A.