发明名称 |
Methods of investigating, diagnosing, and treating amyloidosis |
摘要 |
The present invention provides a therapeutic method for removing amyloid fibrils from a patient. The present invention also provides a transgenic animal that develops systemic AA amyloidosis within three weeks for use as a tool to investigate AA amyloidosis and to evaluate agents that may be potentially useful in preventing and treating amyloid-related disorders. Further, the present invention provides diagnostic assays for monitoring immunoglobulin light chain fibrillogenesis in real-time and for identification of the chemical nature of the protein in amyloid deposits which enables the determination of the type of amyloidosis for therapeutic and prognostic purposes.
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申请公布号 |
US2002019335(A1) |
申请公布日期 |
2002.02.14 |
申请号 |
US20010825872 |
申请日期 |
2001.04.05 |
申请人 |
SOLOMON ALAN;WALL JONATHAN STUART;HRNCIC RUDI;SCHELL MARIA |
发明人 |
SOLOMON ALAN;WALL JONATHAN STUART;HRNCIC RUDI;SCHELL MARIA |
分类号 |
A61K38/17;A61K38/39;A61P25/28;(IPC1-7):A61K38/17;A01K67/027 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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