发明名称 |
N-AMINOSULFONYL BENZAMIDES |
摘要 |
The invention relates to sulfonamide derivatives, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. More particularly the invention relates to a new sulfonamide Nav1.7 inhibitors of formula (I) or a pharmaceutically acceptable salt thereof, wherein Z, R1a, R1b, R2, R3, R4 and R5 are as defined in the description. Nav 1.7 inhibitors are potentially useful in the treatment of a wide range of disorders, particularly pain. |
申请公布号 |
CA2860553(C) |
申请公布日期 |
2016.08.23 |
申请号 |
CA20122860553 |
申请日期 |
2012.12.21 |
申请人 |
PFIZER LIMITED |
发明人 |
BROWN, ALAN DANIEL;GALAN, SEBASTIEN RENE GABRIEL;MILLAN, DAVID SIMON;RAWSON, DAVID JAMES;STORER, ROBERT IAN;STUPPLE, PAUL ANTHONY;SWAIN, NIGEL ALAN |
分类号 |
C07D213/74;A61K31/165;A61K31/277;A61K31/44;A61K31/506;A61P29/00;C07B59/00;C07C307/04;C07C307/06;C07D205/04;C07D213/643;C07D213/69;C07D237/08;C07D401/04;C07D401/12 |
主分类号 |
C07D213/74 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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