| 摘要 |
Derivatives of thieno[2,3-d]imidazoles of the formula I of the formula sheet in which R1 denotes hydrogen, lower alkyl, chlorine, bromine, acetyl, cyclopropylcarbonyl, methoxycarbonyl or ethoxycarbonyl, R2 denotes hydrogen or lower alkyl, R3, R5 and R6 independently of one another denote hydrogen or lower alkyl, R4 denotes hydrogen or lower alkoxy and n denotes 0 or 1, and their pharmaceutically tolerable acid addition salts, a process for their preparation and pharmaceutical preparations which contain these compounds are described. The novel compounds cause a blockade of (H<+> + K<+>) ATPase and can be used as active substances for medicaments for the treatment and prophylaxis of diseases which are caused by increased gastric secretion. |
