发明名称 |
PROCOLLAGEN ASSEMBLY |
摘要 |
A method of producing a desired procolagen or derivative thereof in a system which co-expresses and assembles at least one further procollagen or derivative thereof. The gene(s) for expressing pro-.alpha. chains or derivatives thereof for assembly into the desired procollagen has or have been exogenously selected from natural pro-.alpha. chains or exogenously manipulated such as to express said pro-.alpha. chains or derivatives thereof with domains which have the activity of C-terminal propeptide domains but which will not co-assemble with the C-terminal propeptide of the pro-.alpha. chains or derivatives thereof that assemble to form the said at least one further procollagen or derivative thereof.
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申请公布号 |
CA2282719(A1) |
申请公布日期 |
1998.09.03 |
申请号 |
CA19982282719 |
申请日期 |
1998.03.02 |
申请人 |
THE VICTORIA UNIVERSITY OF MANCHESTER |
发明人 |
BULLEID, NEIL JOHN |
分类号 |
A01K67/027;A61K38/00;A61K48/00;A61P19/00;C07K14/78;C12N15/09;C12N15/12;(IPC1-7):C12N15/12;C12N5/10;C12N15/62 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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