| 摘要 |
A method for treating a patient having coronary and/or peripheral ischemic syndrome by administering to the patient an effective amount of an antithrombotic agent, e.g. a glycoprotein IIb/IIIa antagonist, a thrombin inhibitor, a factor Xa inhibitor, or a low molecular weight heparin, and an effective amount of an angiogenesis promoter, e.g. a vascular endothelial growth factor or a fibroblast growth factor. Administration of the angiogenesis promoters may be by any suitable means known to persons skilled in the art, e.g. via bolus injection, continuous intravenous administration, coated stent implantation and gene transfer, which provides localized or systemic delivery of the angiogenesis promoter at the ischemic tissue. |
