| 发明名称 |
Viral vectors having reduced virulence |
| 摘要 |
The present invention provides recombinant vaccinia virus having a deletion of the region encoding the C-terminal seven amino acids of the E3L gene product and comprising exogenous DNA. Compositions comprising the recombinant vaccinia virus and methods of use thereof are also provided.
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| 申请公布号 |
US2005042206(A1) |
申请公布日期 |
2005.02.24 |
| 申请号 |
US20040830547 |
申请日期 |
2004.04.23 |
| 申请人 |
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发明人 |
JACOBS BERTRAM;LANGLAND JEFFREY;VIJAYSRI SANGEETHA |
| 分类号 |
C12N15/09;A61K35/76;A61K38/00;A61K48/00;C12N7/01;C12N7/04;C12N15/863;C12P21/02;(IPC1-7):A61K48/00;A61K39/29;A61K39/12;C12N15/86 |
主分类号 |
C12N15/09 |
| 代理机构 |
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代理人 |
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