发明名称 ANTI-VASA ANTIBODIES, AND METHODS OF PRODUCTION AND USE THEREOF
摘要 Anti-VASA antibodies (mAbs), particularly humanized mAbs that specifically bind to VASA with high affinity, are disclosed. The amino acid sequences of the CDRs of the light chains and the heavy chains, as well as consensus sequences for these CDRs, of these anti- VASA mAbs are provided. The disclosure also provides nucleic acid molecules encoding the anti-VASA mAbs, expression vectors, host cells, methods for making the anti-VASA mAbs, and methods for expressing the anti-VASA mAbs. Finally, methods of using the anti-VASA mAbs to isolate and/or purify cells expressing VASA are disclosed.
申请公布号 WO2016044436(A3) 申请公布日期 2016.06.09
申请号 WO2015US50449 申请日期 2015.09.16
申请人 OVASCIENCE, INC. 发明人 WEAVER, DAVID, T.;ZHANG, BO
分类号 C07K16/40 主分类号 C07K16/40
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