Organism sample observation device

摘要

A biological specimen observation apparatus whereby observation of a biological specimen can be performed accurately. In macro observation, a biological change region is extracted from a macro image, a micro observation point corresponding to an extracted biological change region is registered, and an object for tracking is identified. In micro observation, it is judged from the micro image whether or not biological change has continued in the biological change region at the micro observation point, and the registered micro observation point is updated on the basis of this judgment result. It is possible to carry out both macro observation for detecting a biological change region and micro observation for observing the progress of growth of a partial minute region where biological change has been exhibited, and to carry out accurate observation of a biological specimen.

主权项

1. A biological specimen observation apparatus which observes temporal change in a biological specimen, comprising:
a first imaging device configured to acquire a fluorescent macro image by capturing an image of a macro region of a broad range of the biological specimen, while time lapse observation is performed; a second imaging device configured to capture an image of a micro region of change in the biological specimen identified at a micro observation point, while the time lapse observation is performed; and one or more processors configured to: determine a location of a biological change region in the acquired macro image based on an image analysis of the macro image, the biological change region representing a region of change in the biological specimen, the image analysis including determining a change in a luminous point of the macro image during the time lapse observation, the biological change region being a region in which the change in the luminous point of the macro image has occurred; register the micro observation point corresponding to the determined biological change region; judge whether or not biological change has continued in the biological change region at the micro observation point, from the acquired micro image; and update the registered micro observation point based on whether or not biological change has continued in the biological change region at the micro observation point.