| 摘要 |
<p>1460916 Preparation of cephalosporin derivatives BRISTOL-MYERS CO 21 Dec 1973 [26 Dec 1972] 23368/76 Divided out of 1460914 Heading C2C The compound I having the D-(-)-configuration in the 7-side chain and salts and esters thereof are prepared by reacting a compound II fully protected by easily cleavable silyl groups with an acylating derivative of an acid III in which B is an amino-protecting group, followed by removal of the protecting groups and optional esterification or salt formation. Pharmaceutical compositions used as antibiotics contain a compound I when prepared by the above process, together with a suitable carrier or diluent.</p> |
