发明名称 Cyclic amine modulators of chemokine receptor activity
摘要 The present invention is directed to cyclic amines of the formula I:(wherein R1, R2, R3, m and n are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-1, CCR-2, CCR-2A, CCR-2B, CCR-3, CCR-4, CCR-5, CXCR-3, and/or CXCR-4.
申请公布号 US6476054(B1) 申请公布日期 2002.11.05
申请号 US20000690622 申请日期 2000.10.17
申请人 MERCK & CO., INC. 发明人 CALDWELL CHARLES G.;FINKE PAUL E.;MACCOSS MALCOLM;MILLS SANDER G.;OATES BRYAN;KIM DOOSEOP;KOTHANDARAMAN SHANKARAN;WANG LIPING
分类号 C07D211/56;C07D211/58;C07D401/06;C07D405/06;C07D409/06;C07D521/00;(IPC1-7):A61K31/445 主分类号 C07D211/56
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