Artificial calibration virus to control HIV viral load tests by PCR in real time
摘要
The present invention refers to the design of an artificial calibrating virus (ACV), as well as a methodology quality guarantee system, which has controlling characteristics in the performance of all the stages carried out during a detection and/or quantification molecular test. More specifically, the referred to ACV is used for the validation and calibration of quantitative determinations of circulating viruses in blood plasma samples by means of polymerase chain reaction (PCR) technology in real time (or ‘real time PCR’).
申请公布号
ZA200900382(B)
申请公布日期
2010.01.27
申请号
ZA20090000382
申请日期
2009.01.16
申请人
FUNDACAO OSWALDO CRUZ - FIOCRUZ
发明人
FERREIRA, ANTONIO GOMES PINTO;FERREIRA, JOSE ANTONIO PINTO DE SA;TANURI, AMILCAR;BRINDEIRO, RODRIGO DE MORAES BRINDEIRO;BRINDEIRO, PATRICIA ALVAREZ BAPTISTA