CONJUGATES OF RGD PEPTIDES AND PORPHYRIN OR (BACTERIO)CHLOROPHYLL PHOTOSYNTHESIZERS AND THEIR USES
摘要
Conjugates of porphyrin, chlorophyll and bacteriochlorophyll photosensitizers with RGD-containing peptides or RGD peptidomimetics are provided that are useful for photodynamic therapy (PDT), particularly vascular-targeted PDT (VTP), of tumors and nonneoplastic vascular diseases such as age-related macular degeneration, and for diagnosis of tumors by different techniques.
申请公布号
WO2008023378(A1)
申请公布日期
2008.02.28
申请号
WO2007IL01055
申请日期
2007.08.23
申请人
YEDA RESEARCH AND DEVELOPMENT CO. LTD;SCHERZ, AVIGDOR;SALOMON, YORAM;RUBINSTEIN, EFRAT;BRANDIS, ALEXANDER;EREN, DORON;NEIMANN, KARIN
发明人
SCHERZ, AVIGDOR;SALOMON, YORAM;RUBINSTEIN, EFRAT;BRANDIS, ALEXANDER;EREN, DORON;NEIMANN, KARIN