<i>N</i>-[4-(quinolin-4-yloxy)cyclohexyl(methyl)](hetero)arylcarboxamides as androgen receptor antagonists, production and use thereof as medicinal products

摘要

The invention relates to N-[4-(quinolin-4-yloxy)cyclohexyl(methyl)](hetero)arylcarboxamides, intermediates and methods for their production, use thereof for treating and/or preventing diseases and use thereof for producing medicinal products and use thereof for treating and/or preventing diseases, especially of hyperproliferative diseases.

主权项

1. A compound of formula (I)in which
R1 stands for H, cyano, fluorine, chlorine or bromine; A stands for phenyl or 5-membered heteroaryl, wherein the phenyl or the 5-membered heteroaryl is optionally substituted with one, two or three substituents selected independently of one another from:
halogen, cyano, alkyl-, haloalkyl-, cycloalkyl-, heterocyclyl-, hydroxy, alkoxy-, fluoroalkoxy-, cycloalkyloxy-, amino-, alkylamino-, dialkylamino-, cycloalkylamino-, alkylcycloalkylamino-, dicycloalkylamino-, alkylcarbonylamino-, cycloalkylcarbonylamino-, alkylsulphanyl-, cycloalkylsulphanyl-, alkylsulphonyl-, cycloalkylsulphonyl-, aminosulphonyl-, alkylaminosulphonyl-, cycloalkylaminosulphonyl-; and alkoxycarbonyl-; n=0, 1 or 2; or a salt thereof.