| 摘要 |
Benzanilide derivatives of the formula: <CHEM> wherein R<1> is alkyl optionally containing double or triple bonds, and optionally interrupted by one or more hetero atoms; R<2> is hydrogen, methyl, or ethyl; R<3> is halogen, alkyl, -OY, -SOnY, or dimethylamino; R<4> and R<5> are hydrogen, alkyl or (CH2)m-Z, wherein: (i) Z is -OCH3, -SOqCH3, -N(CH3)2 or alkanoylamino, and m is 2, 3 or 4; or (ii) Z is heterocyclyl and m is 0, 1, 2, 3, or 4; X is oxygen, -OCH2-, -SOp-, -SOpCH2- or -NR<6>-; R<6> is hydrogen, methyl, ethyl, or acyl; Y is alkyl; and n, p and q are each 0, 1, or 2; are useful as anti-atherosclerotic agents. |
