发明名称 |
Waveguide immunosensor with coating chemistry and providing enhanced sensitivity |
摘要 |
Methods and apparatus for evanescent light fluoroimmunoassays are disclosed. The apparatus employs a planar waveguide and optionally has multi-well features and improved evanescent field intensity. The preferred biosensor and assay method have the capture molecules immobilized to the waveguide surface by site-specific coupling chemistry. Additionally, the coatings used to immobilize the capture molecules provide reduced non-specific protein adsorption.
|
申请公布号 |
US5846842(A) |
申请公布日期 |
1998.12.08 |
申请号 |
US19960640141 |
申请日期 |
1996.04.30 |
申请人 |
UNIVERSITY OF UTAH RESEARCH FOUNDATION |
发明人 |
HERRON, JAMES N.;CHRISTENSEN, DOUGLAS A.;CALDWELL, KARIN D.;JANATOVA, VERA;HUANG, SHAO-CHIE;WANG, HSU-KUN |
分类号 |
G01N21/25;G01N21/55;G01N21/64;G01N21/77;G01N33/543;(IPC1-7):G01N33/543;G01N33/552 |
主分类号 |
G01N21/25 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|