6,5-HETEROBICYCLIC DERIVATIVES, PHARMACEUTICAL COMPOSITION BASED THEREON AND METHOD OF TREATING DISEASES

摘要

This invention relates to compounds of formula (I), wherein the dashed lines represent optional double bonds; A is nitrogen or CR<7>; B is -NR<1>R<2>, -CR<1>R<2>R<10>-C(=CR<2>R<11>)R<1>, -NHCR<1>R<2>R<10>, -OCR<1>R<2>R<10>, -SCR<1>R<2>R<10>, -CR<2>R<10>NHR<1>, -CR<2>R<10>OR<1>, -CR<2>R<10>SR<1> or -COR<2>; J and K are each independently nitrogen or carbon and both J and K are not nitrogens; D and E are each selected, independently, from nitrogen, CR<4>, C=O, C=S, sulfur, oxygen, CR<4>R<6> and NR<8>; G is nitrogen or carbon; and their use for the prevention or inhibition of a disorder that can be treated by antagonizing CRF.